How Modvigil 200mg Helps With Shift Work Sleep Disorder
Modafinil (Provigil) is a wakefulness-promoting agent used to treat excessive sleepiness due to narcolepsy or shift work sleep disorder. It is also used to improve sleep cycles in patients with obstructive sleep apnea.
Results from this study support the hypothesis that cognitive performance is impaired following a night-shift work shift. Moreover, subjective ratings of mood and alertness are modified by shift condition.
Dosage
Modvigil 200 mg is a powerful wakefulness medication used to treat conditions such as narcolepsy, obstructive sleep apnea and shift work sleep disorder. It works by changing the amounts of certain natural substances in your brain that control sleep cycles and wakefulness. It is typically prescribed at a dose of 200 mg taken once daily. Occasionally, doctors may prescribe higher or lower doses for these conditions depending on your condition and health needs.
The purpose of this study was to investigate the effects of a single oral dose of modafinil on cognitive/psychomotor performance, mood and measures of sleep in patients with chronic shift work sleep disorder (SWSD). This was a double-blind, within-participant study using a 23-day residential laboratory design.
Participants received a placebo or either 200 or 400 mg of modafinil in the morning before their night shift. Subjective ratings of alertness were significantly improved at both modafinil doses during the simulated night shift condition. In addition, improvements in sleep latency and quality were observed at both modafinil doses.
Modafinil has also been shown to improve symptoms in obstructive sleep apnea, and can be used off-label to reduce fatigue in people with multiple sclerosis or depression. It is important to remember that this medication carries a risk of misuse. If you think that you or someone you know is misusing the drug, talk to your doctor right away.
Side Effects
Modafinil 200 mg can help improve your sleep cycle and alleviate the symptoms of shift work sleep disorder. It can also be used to treat narcolepsy and obstructive sleep apnea. It works by promoting wakefulness and increasing dopamine activity in the brain.
It can also be used off-label to reduce fatigue in patients with multiple sclerosis and depression. It can be taken as a single dose or in combination with other medications. It is important to understand the side effects of Modafinil 200mg and how it can interact with other medications.
In healthy research volunteers who reported waking episodes of excessive sleepiness associated with shift work, both the 200 and 400 mg doses of modafinil increased ratings of alertness compared with placebo.
However, the 400 mg dose significantly increased sleep onset latency on night three of night-shift work (p0.004). The other subjective-effect ratings and measures from the DEQ were not altered significantly as a function of drug condition.
The findings indicate that the stimulant properties of modafinil may be helpful in treating individuals with shift work sleep disorder and in reducing resulting impairments in performance. Although the results are encouraging, it is important to note that the study was small and was conducted in healthy research volunteers. In addition, the procedures simulated work-shift disruptions, rather than a clinically relevant scenario.
